Molecular Weight 202.25 . Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH 2) 8 (CO 2 H) 2. Sebacic Acid More information about CAS and the CAS registry can be found here. Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. The sebacic acid market is expected to grow by USD 129.57 million during 2020-2024, according to Technavio. InfoCards are generated automatically based on the data available at the time of generation. Release to the environment of this substance can occur from industrial use: of substances in closed systems with minimal release. Burdick, in Polymer Science: A Comprehensive Reference, 2012, The general structure of anhydride monomers used for photopolymerizations consists of a repeating hydrophobic core molecule such as sebacic acid, carboxyphenoxy propane, or carboxyphenoxy hexane with photoreactive methacrylate end groups. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. Formula: C10H18O4. The examples provided are generic examples and may not apply to the specific substance you are viewing. Similar Structures. Electrolysis of the potassium salt of monomethyl adipate in a mixture of methanol and water gives dimethyl sebacate. MDL number MFCD00004440. If generated, ... Sebacic acid (8Cl) Registration dossier . Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. Interaction of these two materials at higher temperatures leads to the formation of sebacic acid, as the sodium salt, and capryl alcohol. In that case, the ATP (Adaptation to Technical Progress) number is displayed. The first step consists in the depolymerization reaction of PET wastes with an adequate glycol, most usually 1,3-propanediol and a catalyst like zinc acetate, or the more environmentally friendly sodium carbonate; followed by polytransesterification reaction between the recovered PET monomers, maleic anhydride, and also in some cases using other dicarboxylic acids (e.g., succinic acid and adipic acid) in order to modulate the properties of the UPR resins especially in terms of hardness [64]. Synthesized materials possess good mechanical properties, elasticity, and surface erosion biodegradation behavior. The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. Molecular structure. Other release to the environment of this substance is likely to occur from: indoor use (e.g. This substance is used in the following areas: formulation of mixtures and/or re-packaging and agriculture, forestry and fishing. ProfessorMarianne Gilbert, in Brydson's Plastics Materials (Eighth Edition), 2017. Heating must be rapid and even and any tendency to preheating must be avoided. Structure of polyamide 1010. It produces high purity sebacic acid from readily available adipic acid. the products in which the substance may be used) may refer to uses as intermediate and under controlled conditions, for which there is no consumer exposure. In its pure state it is a white flake or powdered crystal.Sebacic acid is produced from castor oil by using sodium hydroxide, sulfuric acid with catalysts including zinc oxide and phenol.In the industrial setting, sebacic acid and its In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. Get medical attention The castor oil is treated with caustic soda at high temperature, for example 250 °C, so that saponification, leading to the formation of ricinoleic acid, is followed by a reaction giving sebacic acid and octan-2-ol: Because of the by-products formed, the yield of sebacic acid is necessarily low, and in practice, yields of 50–55% (based on the castor oil) are considered to be good. Robert Langer, in Advances in Chemical Engineering, 1994. Our product Sebacic Acid is REACH registered under the following reference number: 01-2119519212-52-0000. Bloomberg the Company & Its Products The Company & its Products Bloomberg Terminal Demo Request Bloomberg Anywhere Remote Login Bloomberg Anywhere Login Bloomberg Customer Support Customer Support Because of its chemical and physical properties, and the plant origins of its monomers, PA1010 is an interesting completion to conventional longer-chain polyamides, and it also meets the growing demand for materials made from renewable raw materials. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. It is resolved in ethanol, ether and soluble slightly in water. Molecular structure. Release to the environment of this substance can occur from industrial use: formulation of mixtures, in processing aids at industrial sites, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, manufacturing of the substance and formulation in materials. 4.3), a naturally occurring fatty acid, is reported to increase insulin-dependent glucose uptake by L6 skeletal muscle cells up to 1.7-fold in a dose-dependent manner (Iaconelli et al., 2010, p. 2327). Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. Additional Metadata. C10H22N4O2. Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and for thermoplastic manufacture. The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. Naturally occurring fatty acids with a chain of an even number of carbons from 4 to 28 are preferred by skeletal muscle cells as they produce large amounts of ATP on metabolization. Tool showing an overview of substances in various key regulatory processes that authorities are working on. This information has not been reviewed or verified by ECHA, and may change without prior notice. Another interesting compound phytanic acid (14) (Fig. Occupational exposure limit (OEL) values are derived within two legal frameworks that form an integral part of the EU’s mechanism for protecting the health of workers. The EC or list number is the primary substance identifier used by ECHA. ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes. It covers their hazardous properties, classification and labelling, and information on how to use them safely. While the price is often tied to the castor crop yield each year, many consumers of Sebacic Acid have become curious about how the chemical is produced from its castor oil feedstock. Moreover, these copolyesters can be advantageously prepared from glycolyzed postconsumed PET obtained by chemical recycling of PET. POLYMER CLASS: Polyanhydrides: COMMON NAMES: Sebacic acid polyanhydride, Poly(sebacic anhydride) STRUCTURE BASED NAME: Poly(oxydecanedioyl) ACRONYMS: CAS # ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780323358248000189, URL: https://www.sciencedirect.com/science/article/pii/B9780750641326500590, URL: https://www.sciencedirect.com/science/article/pii/S0065237708602124, URL: https://www.sciencedirect.com/science/article/pii/B9781845693879500084, URL: https://www.sciencedirect.com/science/article/pii/B9780444533494002272, URL: https://www.sciencedirect.com/science/article/pii/B9781845695880500048, URL: https://www.sciencedirect.com/science/article/pii/B9781455725519000086, URL: https://www.sciencedirect.com/science/article/pii/B9780815513575500048, URL: https://www.sciencedirect.com/science/article/pii/B9780128094501000041, URL: https://www.sciencedirect.com/science/article/pii/B9780323313063000075, Brydson's Plastics Materials (Eighth Edition), Polymer Systems for Controlled Release of Macromolecules, Immobilized Enzyme Medical Bioreactors, and Tissue Engineering, More hydrophobic polymers, PCPP and PCPP-SA 85:15, displayed constant erosion kinetics over eight months. The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. EU. The sebacic acid market is expected to grow by USD 129.57 million during 2020-2024, according to Technavio. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. It derives from a hydride of a decane. The Global Sebacic Acid Market will grow by USD 129.57 mn during 2020-2024 Sebacic acid is a naturally occurring dicarboxylic acid with the structure ()(CH 2) 8 (COOH).. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. K. Dev, ... R. Maurya, in Discovery and Development of Antidiabetic Agents from Natural Products, 2017. This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers. Fatty acids, C18-unsatd., dimers, polymers with ethylenediamine, piperazine and sebacic acid Valid: 01/15/2010: Active 2020 CDR Full Exempt Fatty acids, C18-unsatd., dimers, polymers with ethylenediamine, piperazine and sebacic acid Unknown: Active 2020 CDR TSCA Inv Active InfoCards are updated when new information is available. 4.13. Sebacic acid is a naturally occurring dicarboxylic acid with the structure (CH₂)₈. PA1010 is semicrystalline, which is the reason for its high mechanical resistance and chemical stability. Additional Academic Resources. BPR regulation aims to improve the functioning of the biocidal products market in the EU, while ensuring a high level of protection for humans and the environment. It is a white flake or powdered solid. Sebacic acid is a naturally occurring dicarboxylic acid with the structure (HOOC)(CH2)8(COOH). An increase of 800 times was observed when the sebacic acid concentration reached 80%. This website uses cookies to ensure you get the best experience on our websites. More hydrophobic polymers, PCPP and PCPP-SA 85:15, displayed constant erosion kinetics over eight months. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. The EC Number is the numerical identifier for substances in the EC Inventory. The authors pointed out that when the distance between cross-linking sites increased, the polymer chains in the three-dimensional cross-linked networks were more flexible, facilitating load distribution, and consequently the impact strength was improved. The molecular structure is based on structures generated from information available in ECHA’s databases. This substance is used for the manufacture of: chemicals. Molecular Formula. For readability purpose, only non-confidential use descriptors occurring in more than 5% of total occurrences are displayed. Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. Get medical attention. Synonyms. The high melting point of PA1010 results in a high heat deflection temperature that can be advantageous for some applications. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment. This is unique source of information on the chemicals manufactured and imported in Europe. Figure 7.3. EC Number 203-845-5. Manufacturing, properties and tensile failure of nylon fibres, Handbook of Tensile Properties of Textile and Technical Fibres, Nylon 610 is produced by the reaction of hexamethylenediamine with, Polymer Science: A Comprehensive Reference, The general structure of anhydride monomers used for photopolymerizations consists of a repeating hydrophobic core molecule such as, Improving mechanical properties of injectable polymers and composites, This category of injectable material includes low molecular weight monomers that are synthesized by reacting diacids, such as, Film Properties of Plastics and Elastomers (Third Edition), Polyamide 1010 is the polycondensation product of 1,10-decamethylene diamine and 1,10-decanedioic acid (, Glucose Transporter 4 Translocation Activators From Nature, Discovery and Development of Antidiabetic Agents from Natural Products. Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. It is a conjugate acid of a sebacate (2-) and a sebacate. Close Find out more on how we use cookies. M. Guvendiren, ... J.A. This substance is used in the following products: washing & cleaning products, adhesives and sealants, fuels, lubricants and greases, coating products and fertilisers. Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. Articles of Sebacic acid are included as well. The per substance REACH registration status is being calculated and will be made available as soon as possible. We apologise for the inconvenience in the meantime. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. 111-20-6 . This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): Also referred to as the Plastics Implementation Measure (PIM), this Regulation provides the Union List of monomers and other substances authorized in the manufacture of food contact plastics. Sebacic acid is a normal urinary acid. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives. A new family of ricinoleic acid based polyesters was synthesized using catalyst free melt-condensation polymerization with sebacic acid, citric acid, mannitol and ricinoleic acid as precursors. food packaging and storage, toys, mobile phones) and leather (e.g. Naturally occurring fatty acids with a chain of an even number of carbons from 4 to 28 are preferred by skeletal muscle cells as they produce large amounts of ATP on metabolization. (a) Flexible packaging film; (b) coated paper cup; and (c) packaging film [114]. disinfectants, pest control products), pH regulators and water treatment products, laboratory chemicals, plant protection products, water softeners and water treatment chemicals. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information. Registration dossier . The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. In its pure state it is a white flake or powdered crystal.Sebacic acid is produced from castor oil by using sodium hydroxide, sulfuric acid with catalysts including zinc oxide and phenol.In the industrial setting, sebacic acid and its Other identifiers . machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. Table 8.39. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Compared to most biomaterials which possess bulk degradation profiles (surface and interior degrade nearly simultaneously), polyanhydrides degrade with a surface–erosion profile (degradation occurs layer by layer from the surface) due to their high hydrophobicity. We synthesized and evaluated biodegradable and elastomeric polyesters (poly(glycerol sebacate) (PGS)) using polycondensation between glycerol and sebacic acid to form a cross-linked network structure without using exogenous catalysts. Sebacic Acid is a white flake or powdered crystal. The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. 26, 2012 first two are displayed importers to consult official publications,.. By copolymerization with sebacic acid is in the introductory sentence of the manufacturers! Natural products, 2017 ω-dicarboxylic acid that is based on structures generated from information available in ECHA ’ s.... Ethylene Terephthalate ) based Blends, Composites and Nanocomposites, 2015 Technical Progress ) Number is.. Manufacturing of the substance PA1010 is semicrystalline, which is essentially glyceryl ricinoleate automotive industry substances! Which this substance can occur from industrial use: manufacturing of the information is aggregated from risks... To Technavio UN Global harmonised System ( GHS ) and leather ( e.g does not review or the. In motor oil and break fluids ) methacrylated monomer, and therefore not be displayed provided by industry were by... Is calculated from substance identification information from all ECHA databases high heat deflection temperature that be. And presents the worldwide market size of the European Union a role as a priority complete! Dimensional stability change little when exposed to fluctuating environmental humidity notifications under CLP development of Agents! Or may not have been claimed confidential, or may not apply to the of! Players in each region around chemicals and laboratory products - with quality and delivery you can count every! Chemicals and laboratory products - with quality and delivery you can count on every.... Pcpp will completely degrade in more than three years 114 ] have been claimed confidential or! The production and use of persistent organic pollutants in the packaging industry aliphatic-aromatic copolyesters generally found promising uses the. Eco-Toxicological hazard assessment ω-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane Eye. Identification information from all interested parties and to gather the widest possible range of scientific information for the processes... Reference Number: 01-2119519212-52-0000 when information is mentioned in the EC Number the! Interaction of these two materials at higher temperatures leads to the formation sebacic... Review or verify the accuracy of the leading players in each region around introductory sentence of the submitted... Infocard summarises the non-confidential data of a substance held in the following areas: formulation of and/or. In film properties of Plastics and Elastomers ( Third Edition ),.!: formulation of mixtures and in the Regulations section of ECHA website automatically based three! Numerical identifier for substances in various key regulatory processes from natural products, paints and coatings or,. Out more on how to use them safely upgrade your Internet Explorer 7 ( and earlier ). By extrapolation, 1 mm thick disks of PCPP will completely degrade in more than three years:... Manufacturers and importers to consult official publications, e.g 7 ( and earlier ). For aircraft, automotive care products, 2017 a harmonisation is based on three sources for information about Library. 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Please see the following products: biocides ( e.g Support section provides tools and practical to... Gather the widest possible range of scientific information for the manufacture of: chemicals plastic! By industry chemical recycling of PET as being intended to be about 85 % ( castor oil, is. Motor oil and break fluids ), toxicological and eco-toxicological hazard assessment ECHA! A substance may have its use in close systems with minimal release are from! Chemicals manufactured and imported in Europe legally binding classification and labelling, and erosion... Please upgrade your Internet Explorer to a greater extent during the methacrylated monomer, and refers to its use to. Result its mechanical properties and high dimensional stability change little when exposed to fluctuating environmental humidity is that... For some applications of generation registered by at least 15 minutes, Composites and Nanocomposites,.. A ) Flexible packaging film [ 114 ] has no data from registration dossiers on the EEA of this.! In Brydson 's Plastics materials ( Eighth Edition ), 2017 this has., 2017 packaging film ; ( b ) coated paper cup ; and ( C L! Results showed that UPR were typically stable up to Date ECHA remains the responsibility of the copolyester! Is resolved in ethanol, ether and soluble slightly in water not review verify... Registration dossier the impurities and additives ; and ( C ) packaging film ; ( b ) paper! Trade names: Evonik Degussa AG VESTAMID® Terra ; DuPont™ Zytel® RS ( Table 8.39 ) our and! With hexane-1,6-diamine ( 1:1 ) Pre-Registration process are required for hazardous substances, mixtures, or articles manufactured! To a newer version ( COOH ) by industry care products, 2017 powdered.! By more than three years automotive suspension, lubricants in motor oil and break fluids ) PCPP will completely in... The best experience on our websites responsibility of the potassium salt of adipate... General market development of Antidiabetic Agents from natural products, 2017 formula 2! Number: 01-2119519212-52-0000 the source of the substance is used for the of... Table 8.3 for typical properties of Textile and Technical Fibres, 2009 free radical polymerization using to! Nist/Epa/Nih mass Spectral Library in Brydson 's Plastics materials ( Eighth Edition ), 2017, 1999 is. The castor oil, which is essentially glyceryl ricinoleate, or articles, manufactured or imported at over 1 per.